The invention relates to the field of the aseptic transfer of biopharmaceutical products between a container and a closed chamber.
Alternatively, the valve may comprise a portion of a female connector and the filling device may comprise a portion of a male connector to form an aseptic fluid connector for the aseptic transfer of fluid therethrough.
This allows the filter element (34) to be steam sterilized in situ and avoids the need for steam autoclaving and aseptic transfer.
The invention also relates to a method of aseptic transfer of a quantity of liquid from a first space (1) containing such liquid under a given pressure to a second space (2).
Asceptic transfer through a needle penetrating a septum is accomplished by inserting an elongate inner tube through the needle and delivering a product fluid through the inner tube.