A freeze-dryer and method of controlling the same is provided.
Said machine is designed to handle and store glass bottles of pharmaceutical products in a multilevel freeze-dryer.
The invention relates to a freeze-dryer, wherein the frozen goods can be suitably processed by means of frozen goods covers.
Further, a transfer section (308) is provided for a product transfer from the spray chamber (302) to the freeze-dryer (304).
The method is also useful to sterilize a containersuch as a lyophilizer before introducing the products.
The present invention includes a freeze dryer (10) which has a housing defining a chamber (12).
A freeze dryer processes bulk powder products.
The ventilator (16) comprises a cabinet (22) located over the slot door (30) of the freeze dryer (10), a front wall (24) of the cabinet (22) facing the freeze dryer (10).
A loading system for a freeze dryer (10) or the like comprises a plurality of transfer frames (36) each for surrounding a batch of containers to be loaded into the freeze dryer (10).
The first and second transfer frames (36) are then moved on to the shelf (20) of the freeze dryer (10).
Movement of a slot door of a freeze dryer is driven by a rack and pinion actuator.
A freeze dryer has a vacuum pump which is connected directly to a drying chamber without the use of a cold trap condenser.
A freeze dryer (10) comprises a chamber (12) housing a plate (22) from which a plurality of shelves (20) is suspended.
A ventilator (16) for controlling the local environment external to s slot (13) of a freeze dryer (10) is described.
Thus, when the slot door (30) is raised to open the slot (13), only air from this controlled air stream enters the freeze dryer (10).
A freeze dryer (10) comprises a chamber (12) having a rectangular slot through which vials are inserted into the chamber (12).
The freeze dryer freezes the product by mixing an atomized spray of product with sterile liquid nitrogen.
This invention is directed to freeze dryers used in the pharmaceutical industry, and in particular, to a barrier system for freeze dryers located in an isolator or clean room facilitate sterilization of the isolator.
An integrated heater/cooler for heating and cooling of heat transfer fluid in a freeze dryer is provided.
A freeze dryer comprises a chamber (16) having a rectangular slot (14) through which vials are inserted into the chamber, and a slot door (12) for forming a seal with the chamber to close the slot.
A freeze dryer shelf (10) comprises opposed, parallel first and second plates (12, 14) having at least one flow channel (18) located therebetween for conveying a diathermic fluid between the plates.
An assembly for loading the chamber (12) comprises a bar (32) extending across the slot to engage vials to be inserted into the chamber (12).
A moveable bridge plate is positioned between a shelf (20) of the freeze dryer (10) and the chamber loading position to receive a first loaded transfer frame (36) from the transport table (60).
In order to use liquid collagen as a medical material, the collagen is enriched to high concentration using tangential flow filtration (TFF), a rotary evaporator, a centrifugal separator or a freezing dryer.
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