Certain of the disclosed peptides have therapeutic use for inhibiting angiogenesis, inhibiting tumor growth, inducing apoptosis, inhibiting pregnancy or inducing weight loss.
The compounds of the invention may inhibit retroviral reverse transcriptases and thus inhibit the replication of the virus.
Sulphonamide derivatives that are useful in the inhibition of metalloproteinases and in particular in the inhibition of TNF-α Converting Enzyme (TACE).
These sialyltransferases are usable as drugs for inhibiting cancer metastasis, preventing viral infection, inhibiting inflammation and potentiating nerve tissue.
Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells.
The nucleic acid molecule capable of inhibiting the expression according to the present invention can inhibit the expression of periostin gene.
These compounds are excellent in the effects of inhibiting cerebral edema, particularly ischemic cerebral edema, and inhibiting delayed neuron death (or inhibiting calcium inflow into neuros).
The inhibitor can inhibit the action of the enzyme.
The antitumor agent is useful for inhibiting tumor growth, inhibiting tumor angiogenesis and treating diseases associated with neovascularization.
Thus, invention compounds can be used to inhibit cell growth alone or be used in combination with a nucleic acid damaging treatment to inhibit cell growth.
The present invention provides compositions and methods useful for inhibiting the activity of ErbB3 and ErbB4, inhibiting neoplastic growth, or increasing nerve growth.
A motor stator barrier (56) can inhibits fluid flow into the motor stator (90) , and a rotor barrier (112) can inhibits fluid flow into the motor rotor.
In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells.
Such targeting is effective to inhibit natural mRNA splice processing, produce splice variant mRNAs, and inhibit normal expression of the protein.
The compound and extracts are useful to inhibit the growth of endothelial cells and to inhibit vascularization in a tissue.