The present invention relates to the process for the conversion of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (II), to the 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (I).
Disclosed are processes for preparing compounds of formula I, the compounds are useful as intermediates for preparing indazole and azaindazole substituted compounds.
The invention is directed to 6-(4-pyrimidinyl)-1 H-indazole derivatives.
The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.
The present methods are useful for preparing indazole-3-carboxylic acid on scaled-up levels.
lndazole-3-carboxamide compounds for treating various diseases and pathologies are disclosed.
In the formula azolN-CH¿2?CH2-N (CH2CO2R)¿2 (I), azol is pirazol; 3,5-dimethylpirazol; indazol; etc. and R is alkyl or H or Na.
The 6-benzyloxy-1-(2-hydroxypropyl)indazole can then be transformed into 1-(2-azidopropyl)-6-benzyloxyindazole which in turn can be converted to the final product.
Pyrazolo[3,4-f]indazole-3,7-dione derivatives are useful in prophylaxis and treatment of influenza virus infection.
The present invention relates to novel polymorphic forms of 6-[2 (methylcarbamoyl)phenylsulfanyl]-3-E-[2-(pyridin-2-yl)ethenyl]indazole, and to processes for their preparation.
Provided is an industrially advantageous process for the preparation of indazoleacrylic acid derivatives useful as IKur blocker.
The present invention is directed to indazole compounds for use in the treatment or prevention of influenza virus infection.
Indazole compounds, processes for their preparation, pharmaceutical compositions containing such compounds and their use in therapy.
The invention also relates to the use of an indazole for preparing a pharmaceutical composition that is active in the treatment of neuropathic pain.
The present teaching provide indazole compounds represented by Structural Formulae (I) or (I') or a pharmaceutically acceptable salt thereof.