A hybrid gene incorporating a DNA fragment containing a gene coding for an insecticidal protein, more specifically a gene coding for an endotoxin active against Diptera is described.
The hybrid gene is transferred to a recipient cell wherein the hybrid gene replicates by reverse transcription and is inserted into the recipient cell's genome.
The form of cancer to be treated is preferably malignant haematopoietic damage, particularly involving overexpression of gene ABL1 or having a hybrid gene of which gene ABL1 is a component part, e.g. BCR-ABL1 o NUP-ABL1.
When expressed in a bacterial host, the resulting hybrid gene produces a fusion protein in recoverable yield.
A chimeric bcl-2/IgH antisense transcript that hybridizes with the pre-mRNA of a hybrid gene in t(14;18) translocated cells.
The construct is useful for visualization of intracellular information.
A gene conversion construct and a method of transmitting gene mobility from one cell to the daughter cell, and various uses of the gene-conversion construct are described.
The genetic vaccine construct is for treatment of prostate cancer.
The genetic vaccine construct may also encode for one or more cytokines.
A labeled construct is shown to serve as a marker for identity of the quiescent cells within the meristem.
A single 3' termination sequence, such as a polyadenylation sequence when the construct is to be expressed in eucaryotic cells, follows the last coding sequence.
The present invention relates to a method for orientation-directed construction of a construct comprising at least two nucleic acid segments of interest.
The methods comprise introducing into the plant a recombinant construct that provides for the inhibition of expression of αl,3-fucosyltransferase (FucT) and β 1,2-xylosyltransferase (XyIT) in a plant.
A nano-capsule construct for imaging and therapeutic uses and method for production are provided.
As an alternative to the crossing step, a re-transformation of a transgenic plant line with a second construct can also be performed.
Also provided is a recombinant nucleic acid sequence, a recombinant construct, an expression system and a plant cell comprising the promoter, variant or functional equivalent thereof.