The cyanine can be a symmetrical or unsymmetrical streptocyanine, hemicyanine, closed chain cyanine, or combinations thereof.
The cyanine is preferably substituted with one or more groups that minimize or prevent aggregation of the cyanine and/or inhibit binding of the cyanine to duplex DNA.
Cyanine compounds having the general formula I, conjugates, complexes, and compositions comprising the cyanine compounds are provided.
Preferably the fluorescent labelling reagent is a cyanine dye.
The dye used may be a cyanine dye.
The fluorophore is usually a cyanine dye with varaible substituents.
A conjugated chain beta-N-substituted pentamethine cyanine fluorescent dye is provided.
Samples labelled with cyanine dyes can be used in conjunction with the protein array.
The invention relates to a family of compounds that comprise fluorescent cyanine dyes.
Cyanine dyes with improved fluorescence intensity and photostability.
Hydroxamate substituted azaindoline cyanine dyes, conjugates thereof and methods of using the same are provided.
The subject cyanine dyes include an azaindoline ring having a hydroxamate substituent.
The dye-peptide conjugates include several cyanine dyes with a variety of bis- and tetrakis(carboxylic acid) homologues.
Disclosed are cyanine dyes having meso-substituents in the polymethine chain linking the heterocyclic ring systems.
The linkers form the cyanine dimer compounds by attaching to the pyridinium or quinolinium moiety of the monomer moieties.
The inventive data carrier is further characterized in that at least one cyanine dye is used as the light-absorbing compound.
Disclosed are cyanine dyes that are useful for labeling and detecting biological and other materials.
There is provided a cyanine dye having at least one specified atomic group in each molecule.