Antibodies and autoantibodies are bound, and a precipitated or bound antigen-antigen or antibody-autoantibody complex is formed.
ENOX2 autoantibodies enable cancer screening based both on autoantibody detection and autoantibody dissociation to allow for standard ELISA development as well as therapy.
Disclosed is an autoantibody production inhibitor which can inhibit an autoantibody specifically and can prevent or treat autoantibody autoimmune diseases effectively.
In one embodiment, the antibody is an autoantibody.
The supernatant or surrounding fluid of the bound or precipitated antigen-antigen or antibody-autoantibody complex is then removed.
The present invention encompasses auto-antibodies associated with autoimmune disorders.
These antiparatypical antibodies are, furthermore, used for the treatment of auto-immune diseases against autoreactive cells and relevant auto-antibodies.
The invention relates to a method for identifying an auto-antibody (34), e.g. an auto-antibody against the p53 protein of the tumour suppressor gene p53.
Therapeutic methods include removal of the auto-antibodies by adsorbance or administration of soluble PLA2R or fragments to sequester the auto-antibodies.
Provided are human alpha-synuclein-specific autoantibodies as well as fragments, derivatives and variants thereof as well as methods related thereto.
Binding of the target antigen to the autoantibodies of interest in the biological sample is then detected to ascertain the presence or concentration of the autoantibodies of interest.
Anti-Fas (APO-1, CD95) autoantibodies are found in human sera, which antibodies are biologically functional.
An animal model has been developed for studying the mechanisms of, and screening compounds for the treatment or prevention of, the expression of these autoantibodies.
The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis.
These auto-antibodies prevent binding of HIV viral particles to CD4+ cells.
Disease associated human autoantibodies specific for human thyroid peroxidase are disclosed.
CT antigens are particularly useful for detecting autoantibodies correlated with cancer.
The presence of certain auto-antibodies indicates that a subject has lupus.
The auto-antibodies recognise antigens listed in Table 1 herein.
The presence of certain auto-antibodies indicates that a subject has prostate cancer.
The auto- antibodies recognise antigens listed in Table 1 herein.