perchloric acid solution = 6 g/100 ml
Titration with perchloric acid (US Pharmacopeia 31, Betaine hydrochloride monograph.); or
The volatile nitrogenous bases are extracted from a sample using a solution of 0,6 mol perchloric acid.
In one embodiment, the acid used to precipitate proteinaceous material is perchloric acid, for example, 70 % perchloric acid.
Furthermore a blowing agent mixture is proposed comprising polyols and salts of perchloric acid.
An electrolytic method is used with an electrolyte consisting of perchloric (HC1O4) or sulphuric (H2SO4) acid, 2-50 vol %, in methanol or other organic liquid.
The cell employs concentrated hypochlorous acid as the anolyte and operates at high current density, using a two-stage single oxidation process to produce perchloric acid.
Particularly preferred are the salts of lithium and quaternary ammonium, as well as the salts of perchloric acid, p-toluol sulphonic acid, trifluoromethane sulphonic acid and p-nitrobenzene sulphonic acid.
Figure 2 depicts a graph of the cell voltage at selected current densities for the electrochemical production of perchloric acid from chloric acid.
The present invention relates to a method of using a perchloric acid catalyzed reaction to make acyl derivatives of norprogesterone compounds and, in particular, 16-methylene-17α-hydroxy-19-norpregn-4-ene-3,20-dione.
The electrolyte comprises perchloric (HClO4) or sulphuric (H2SO4) acid, 2-15 vol %, or mixtures thereof in methanol or other suitable organic liquid.
The characteristic feature of the method is that said oxidation is performed with Ce4+ ions, ozone and chromic acid in the presence of perhalogen acid, preferably perchloric acid, at a pH below 3.